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| Week 4 | |||||
| Thursday Oct. 1, 2026 | |||||
| Pittsburgh | 24 | at | 27 | Cleveland | |
| Sunday Oct. 4, 2026 | |||||
| Indianapolis | 30 | at | 13 | Washington | |
| New England | 29 | at | 26 | Buffalo | |
| New York | 12 | at | 23 | Chicago | |
| Jacksonville | 22 | at | 17 | Cincinnati | |
| Arizona | 24 | at | 36 | New York | |
| Los Angeles | 24 | at | 20 | Philadelphia | |
| Green Bay | 17 | at | 14 | Tampa Bay | |
| Tennessee | 18 | at | 24 | Baltimore | |
| Dallas | 34 | at | 30 | Houston | |
| Miami | 10 | at | 15 | Minnesota | |
| Kansas City | 30 | at | 27 | Las Vegas | |
| Denver | 14 | at | 24 | San Francisco | |
| Los Angeles | 23 | at | 30 | Seattle | |
| Detroit | 26 | at | 32 | Carolina | |
| Monday Oct. 5, 2026 | |||||
| Atlanta | 45 | at | 24 | New Orleans | |